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KNCV Tuberculosis Foundation (KNCV) was established in 1903 as an umbrella organization for Dutch tuberculosis control, supporting community-based initiatives across the country and facilitating the exchange of best practices. KNCV was among the founding members of the UNION and STOP TB Partnership. During the 115 years of its existence and to this day KNCV plays a key role in eliminating TB in the Netherlands and supporting high prevalence countries in strengthening and optimizing TB control within national health strategies. In our work three guiding principles apply: Patient-centered care, a programmatic and integrated approach which is always solidly evidence-based.