Triage Test for All Oral DR TB Regimen (TriAD) operational study

Research into new diagnostic approaches for DR-TB.

The TriAD study aims to assess the effectiveness, feasibility, acceptability, and cost effectiveness of the GeneXpert MTB/XDR assay for rapid triage-and-treatment of DR-TB. The TriAD study is operating in Ethiopia, Nigeria and South Africa. KNCV is part of the study consortium, led by the Centre for the AIDS Program of Research in South Africa (“CAPRISA”), and supports the study in Ethiopia. Thus far KNCV has enrolled 28 patients from 5 hospitals in the study.

KNCV also developed a study protocol to assess the feasibility and acceptability (amongst healthcare staff) of the TriAD approach. This protocol will undergo ethical review in early 2023.

Go to the TriAD project website.

KNCV has been fighting TB since its establishment in 1903. Over the past 120 years, the organization has acquired indispensable knowledge and experience in the field of effective TB prevention and care, resulting in pre-elimination in the Netherlands and significant contributions to global evidence generation, policy development and TB program implementation worldwide.

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Tuberculosis is still one of the major causes of preventable death in the world and claims over 4000 lives a day, leading to over 1,5 million deaths a year.

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