The GeneXpert MTB/RIF test from Cepheid HBDC, endorsed by the World Health Organization (WHO) for roll-out in 2010, has tremendous potential for improving TB diagnostic capacity and, as such, TB control in high-burden countries.
The use of the GeneXpert MTB/RIF test is increasing exponentially at a global level. However, resource-constrained countries are faced with some operational difficulties and sub-optimal performance issues. These include, amongst other challenges, the following domains: (i) strategic planning of where to place the GeneXpert MTB/RIF machines; (ii) how to use them in a standardized fashion with a clear diagnostic algorithm; (iii) procurement and supply chain management of GeneXpert MTB/RIF supplies; (iv) required laboratory infrastructure (e.g., UPS, power surge protectors, electricity, air-conditioning, security); (v) training; (vi) routine supervision of laboratory and clinical staff; (vii) monitoring and evaluation of the quality of services (including linkages of the GeneXpert MTB/RIF test result with treatment and treatment outcome);(viii) installation and maintenance; (ix) troubleshooting.
KNCV was appointed as authorized service provider (ASP) for GeneXpert in the year 2014. The major role of KNCV as the ASP is to mitigate the above-mentioned challenges. The Cepheid project covers all GeneXpert in all states in Nigeria (36 + FCT). To achieve part of this broad strategy, KNCV proposes a collaboration with CEPHEID HBDC with a basic service package to support TB control in high-burden and developing countries through National TB control programs, National HIV/AIDS programs and other stakeholders by further ensuring well-functioning GeneXpert MTB/RIF equipment. In 2019, we continued to monitor the project’s Key Performance Indicators to show a reduced repair time for faulty equipment. We organized a stakeholders meeting between Cepheid and the National TB Program to provide lasting solutions including issues of comprehensive & constant warranty coverage and we provided trainings for additional test menus.