Introducing the vaccine to the population

Despite progress in TB control efforts, the global burden of TB remains high, with an estimated 10.6 million new cases and 1.6 million deaths in 2021 alone. New safe, effective, affordable, and accessible TB vaccines could be a game changer in the fight against TB and contribute to the WHO End TB Strategy targets for reduction of disease burden, with the goal of building a world without TB.

However, the successful introduction and scale-up of a new TB vaccine will depend on the readiness of target countries to implement and deliver the vaccine. With approximately 17 TB vaccine candidates in the pipeline, of which six are in phase 3 development and vaccines containing a new class of TB vaccines intended for adolescents and adults, there is an urgent need to assess TB vaccine readiness in target countries.

If a vaccine becomes available, the key challenge will be to ensure that it reaches the populations who most need it. Determining what the best approach will be for introducing the vaccine to the population will be crucial. KNCV contributes to the development of TB vaccines through research, implementation, and health system readiness so we can help pave the way for a successful vaccine rollout to protect the world’s most vulnerable people.

Because investing in TB vaccine research and development can save millions of lives. Therefore is is so important to work together to end TB and ensure that no one is left behind in the fight against this deadly disease.

Ways in which KNCV aims to support TB vaccine readiness:

  • Health systems strengthening
  • Countries’ self-sufficiency and reliance
  • Bridging the gap between frameworks and implementation by identifying the actions necessary to effectively rollout a TB vaccine, once available
  • Ensuring the highest public health impact while taking context and current capacity -spanning from the national to the health facility levels- into account

KNCV has been fighting TB since its establishment in 1903. Over the past 120 years, the organization has acquired indispensable knowledge and experience in the field of effective TB prevention and care, resulting in pre-elimination in the Netherlands and significant contributions to global evidence generation, policy development and TB program implementation worldwide.

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Tuberculosis is still one of the major causes of preventable death in the world and claims over 4000 lives a day, leading to over 1,5 million deaths a year.

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