Publication: Preventive Treatment for Household Contacts of Drug-Susceptible Tuberculosis Patients

Christiaan Mulder, Senior Epidemiologist at KNCV Tuberculosis Foundation, was part of the research “Preventive Treatment for Household Contacts of Drug-Susceptible Tuberculosis Patients”, recently published on Pathogens as part of the Special Issue Mycobacterium tuberculosis Infection: Policy Gaps and Research Breakthroughs.


People who live in the household of someone with infectious pulmonary tuberculosis are at a high risk of tuberculosis infection and subsequent progression to tuberculosis disease. These individuals are prioritized for contact investigation and tuberculosis preventive treatment (TPT). The treatment of TB infection is critical to prevent the progression of infection to disease and is prioritized in household contacts. Despite the availability of TPT, uptake in household contacts is poor. Multiple barriers prevent the optimal implementation of these policies. This manuscript lays out potential next steps for closing the policy-to-implementation gap in household contacts of all ages.

Read full paper here.

Curious about more publications by KNCV staff members? Here you will find a list of the most recent publications.

KNCV has been fighting TB since its establishment in 1903. Over the past 120 years, the organization has acquired indispensable knowledge and experience in the field of effective TB prevention and care, resulting in pre-elimination in the Netherlands and significant contributions to global evidence generation, policy development and TB program implementation worldwide.

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