Good proportion of household contact children age < 5yrs were TB screened but not getting preventive therapy in Ethiopia

E-poster presented during the Union World Conference 2020.

Authors: A. Umar, A. Omer, D. Jerene, D. Lemma, M. Godebo, KNCV Tuberculosis Foundation.

Introduction

Ethiopia made significant strides to improve management of latent tuberculosis infection (LTBI). The recent endorsement of  three-month regimen of  INH and rifapentine (3HP) and 3RH is such an example. In preparation to support the roll out these new recommendations, we reviewed the rate of IPT initiation for eligible under five children in two regions of Ethiopia.

“25-37% of bacteriologically confirmed index TB patients were living with under-five children. Of eligible children screened for TB, only 56% were put on preventive therapy.”

Methods

  • This study was conducted in the Southern and Addis Ababa regions of Ethiopia
  • We collected and analyzed secondary data for the period Oct 2016 – Sept 2017
  • We extracted data from the standard of Care led mentorship database which captured important variables related to contact screening and provision of preventive therapy.

Results

  • 25-37% of bacteriologically confirmed index pulmonary TB patients were living with <5 yr children
  • Of 14716 contacts screened, 11.2% were children
  • 93% of <5-year household contacts were screened for TB but  the diagnosis of TB in a one-time contact TB screening was < 0.15%.
  • Of those screened, 92% were eligible for TB Preventive therapy (TPT) but only 56% received it.

Conclusions

Despite high rates of household contact screening, the rate of TPT initiation was low and information on TPT completion rate is lacking. Further interventions are needed to improve the TPT initiation rate and documentation of TPT completion rates.

Variable SNNPR Addis Ababa Total
N % N % N %
# of HH contact registered 12,727 100% 2,765 100% 15,492 100%
# of HH contact TB screened – all ages 12,102 95% 2,614 95% 14,716 95%
# of HH contact children age < 5 yr 1,417 11.7% 233 8.9% 1,650 11.2%
# of children contacts < 5 yrscreened for TB 1,314 93% 220 94% 1,534 93%
# of < 5 yrcontacts eligible for IPT 1,305 92% 216 93% 1,521 92%
# of eligible children < 5 yr put on IPT 731 56% 116 53% 847 56%

This Project is supported by the Stop TB Partnership’s TB REACH initiative and is funded by the Government of Canada, the Bill & Melinda Gates Foundation, and the United States Agency for International Development.

KNCV has been fighting TB since its establishment in 1903. Over the past 120 years, the organization has acquired indispensable knowledge and experience in the field of effective TB prevention and care, resulting in pre-elimination in the Netherlands and significant contributions to global evidence generation, policy development and TB program implementation worldwide.

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